MegaSporeBiotic™ 180 capsules

MegaSporeBiotic™ 180 capsules

 (13,236 Reviews)

The first all-spore probiotic supplement formulated to support healthy gut microbiome balance.

$161.85
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MegaSporeBiotic™ 180 capsules

MegaSporeBiotic™ 180 capsules

$161.85
$161.85 $171.85
SAVE 5% Sold out
View full details

At a glance 

MegaSporeBiotic features a blend of 5 Bacillus spores. Bacillus spores have a two-phase life cycle, letting them stay dormant through harsh conditions until they reach welcoming environments such as the human gastrointestinal tract.

Once in the large intestine, these dormant spores may transition into their active vegetative forms. This distinctive probiotic blend is formulated to help recondition the gut, differing from strains that struggle to withstand digestion. It is widely trusted by health practitioners and consumers.

  • Vegan/Vegetarian

  • Non-GMO

  • Gluten-Free

  • Free From 9 Major Allergens

  • Made In The U.S. With Globally Sourced Ingredients

    Biological innovation built on thoughtful research

    As pioneers in spore-based probiotics, we focus on careful research and development of the strains featured in formulas like MegaSporeBiotic™.

    Biological innovation built on thoughtful research

    As pioneers in spore-based probiotics, we focus on careful research and development of the strains featured in formulas like MegaSporeBiotic™.

    Thoughtful research. Observed study findings.

    MegaSporeBiotic was evaluated in research looking at occasional abdominal discomfort, alongside digestive wellness for study participants.

     Findings from ten peer-reviewed studies suggest MegaSporeBiotic may support:

    • Greater microbial diversity*
    • Growth of beneficial gut bacteria (and related short-chain fatty acid production)*
    • Helps maintain a balanced profile of naturally occurring flora*

    Whole-body supportive properties

    • Supports microbial diversity*
    • May encourage antioxidant activity*
    • Supports the gut barrier / lining*
    • Supports immune wellness*

    Microbiome Labs develops thoughtful wellness solutions that support balanced, diverse microbiome profiles for whole-body wellness.

    • Science-Driven

      A balance of biological innovation and scientific validation

    • Probiotic Pioneers

      Originators of clinically
      validated spore-based
      probiotics

    • InnovativeBiotechnology

      Evidence-based solutions that help enhance care across health categories

    • Microbiome Optimization

      Committed to whole health through balance and restoration of the gut

      Expand your microbiome knowledge 

      Gain more insight into the microbiome and a deeper understanding of synergistic wellness solutions for practitioner use.

      Micro solutions for macro results 

      Learn how we’re helping change the probiotic industry—since our founding, thousands of practitioners have relied on our groundbreaking products for their patients.

      Access Microbiome Labs products and support 

      When you partner with us, you’re exploring whole-body wellness — seamlessly add our products, access or share educational resources, and receive support across multiple wellness categories.
      Practitioners and patients, keep scrolling.

      For practitioners 

      Create an account to purchase products for your practice or share access so your clients may shop online.

       For patients 

      Create an account using the code shared by your wellness practitioner.
      Don’t have a code? Ask your practitioner about partnering with Microbiome Labs or locate a provider near you.

      Ingredients and formula 

      When MegaSporeBiotic™ was introduced, Microbiome Labs brought a new approach to probiotics. The formula centers on Bacillus spores, shifting the focus toward reconditioning your gut microbiome.

      Bacillus Licheniformis

      Produces full-spectrum B-vitamins and supports a healthy microbial balance in the GI tract.

      Bacillus Indicus HU36™

      Produces key antioxidants right at the site of absorption and supports carotenoid production.

      Bacillus Subtilis HU58™

      Robust spore-former that survives gastric acidity and supports healthy gut immune function.

      Bacillus Clausii

      Highly resilient strain known for supporting microbial diversity and immune balance in the gut.

      Bacillus Coagulans

      Produces L-lactic acid to support optimal intestinal pH and overall digestive comfort.

      Dosing Instructions

      Follow the serving directions on your product label and choose a routine that fits your daily schedule.

      01

      Week 1

      Follow the recommended serving directions.

      02

      Week 2

      Continue following the product label instructions.

      03

      Week 3+

      Maintain a consistent routine according to the label.

      Always read the product label before use. Individual needs and tolerance may vary.

      If you experience discomfort or an unexpected reaction, discontinue use and consult a qualified healthcare professional.

      Do not exceed the recommended serving stated on the product label.

      A smarter way to support gut health

      100% spore-based probiotic*

      Supports gut reconditioning*

      Clinically tested to maintain a healthy gut microbiome*

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       FAQs 

      Microbiome Labs follows quality and testing protocols to help ensure products meet label claims and quality standards. For more information, refer to our quality page.

      Many people stack microbiome supplements, but the best combination depends on your goals and tolerance. A smart approach is to discuss your regimen with your healthcare practitioner to make sure it's right for your needs.

      We pride ourselves on the scientific backing of our products. MegaSporeBiotic alone has 10 human clinical trials on the finished formula. We conduct Real World Evidence studies on our finished products, and our ingredients are some of the most studied probiotics in the world. As part of the Novonesis family, we have access to well-researched bacterial strains and feature them in almost all our formulas.

      Probiotics are beneficial microorganisms. Prebiotics are fibers or compounds that help nourish beneficial microbes. Digestive enzymes help break down food components like proteins, fats, and carbohydrates to support digestion. Many people use them together depending on their goals, diet, and sensitivity.

      Gluten free status varies by product. Check the label and product page for gluten free statements and ingredient disclosures. If you have questions, talk to your healthcare provider.

      Shelf life varies by product. You'll find a "Best by" date printed on every bottle or package. Most of our products have a 24-month shelf life from the date of manufacture. Store them as directed on the label to maintain freshness and potency through that date.

      Traditional probiotics rely on fragile strains that are sensitive to heat, moisture, and stomach acid. MegaSporeBiotic™ is a spore-based probiotic. It uses spore-forming strains chosen for their resilience and compatibility with the digestive environment, so beneficial microbes can reach the gut and support a balanced microbiome.

      In general, probiotics are widely used, but pregnancy and breastfeeding are unique physiological states. It’s best to consult your OB/GYN, midwife, or healthcare provider before starting any supplement to ensure it’s appropriate for your individual needs.

      The QR code lets you confirm your product is authentic, safe, and sourced directly from us. Scan it to verify your product is genuine, check that it hasn't been copied or tampered with, and know it was made to our quality and safety standards.